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The beginning of the Enzyme Industry

The first industrially manufactured enzyme was cheese making rennet that was launched in 1874.

Takadiastase became the first microbially derived enzyme that was marketed as a digestant in 1895.

The industrial use of amylolysis and starch modifying enzymes in malts started in 1902 mainly for desizing.
Standardised swine pancreas derived protease started to be sold in 1907 and immediately came to be in use in the leather industry.

Also in Japan, the production of takadiastase started in 1914 and that of bacterial amylase for desizing started in 1939. Since then, a variety of enzymes have been produced and marketed.

(Please see attached “Enzyme Industrial History In Japan”.) *Japanese only)